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Amerge

naratriptan

By GlaxoSmithKline

What is this medication for?

Naratriptan is used for the relief of migraine attacks with or without aura (warning signs that occur prior to the onset of a migraine). It is not to be used for the prevention of migraine. Migraine headaches are thought to be caused by a widening of the blood vessels in the head. Naratriptan belongs to a class of drugs known as 5-hydroxytryptamine agonists, which relieves migraine headaches by narrowing these vessels.

In most people, naratriptan eliminates or reduces the symptoms of migraine including headache, nausea, vomiting, and sensitivity to light and sound.

Your doctor may have suggested this medication for conditions other than those listed here. As well, some forms of this medication may not be used for all of the conditions discussed here. If you have not discussed this with your doctor or are not sure why you are taking this medication, speak to your doctor. Do not give this medication to anyone else, even if they have the same symptoms as you do. It can be harmful for people to take this medication if their doctor has not prescribed it. Do not stop taking this medication without consulting your doctor.

What form(s) does this medication come in?

Amerge® is available as:

  • tablets
    • 1 mg
    • 2.5 mg
Some medications may have other generic brands available. Always ask your doctor or pharmacist about the safety of switching between brands of the same medication.

How should I use this medication?

Adults: After a headache starts, you take one tablet of naratriptan (1 mg or 2.5 mg). Your doctor can help determine if you should take the 1 mg tablet or the 2.5 mg tablet. Naratriptan should be taken as early as possible after the onset of a migraine headache, but is also effective if taken at a later stage.

If the headache improves after the first dose but then returns, a second tablet may be taken but no sooner than 4 hours after the first tablet was taken. The maximum daily dose of naratriptan is 5 mg in 24 hours.

If the headache does not respond to the first dose, consult with your doctor before you take the second dose. In this situation, a second dose is not likely to work.

It is very important that this medication be taken exactly as prescribed.

Many things can affect the dose of medication that a person needs, such as body weight, other medical conditions, and other medications. If your doctor has recommended a dose different from the ones listed here, do not change the way that you are taking the medication without consulting your doctor.

Store this medication at room temperature, protect it from light and moisture, and keep it out of the reach of children.

Who should NOT take this medication?

Naratriptan should not be used by anyone who:

  • has a history of stroke or transient ischemic attacks
  • has angina (chest pain), including Prinzmetal angina (coronary vasospasm)
  • has blood vessel disease (peripheral vascular disease) including bowel disease
  • has certain types of migraine headaches (including hemiplegic, or basilar migraine)
  • has heart disease or a history of heart disease (e.g., a history of heart attack or silent ischemia [damage to the heart without symptoms])
  • has high blood pressure that is severe or not under control
  • has severely reduced liver or kidney function
  • has taken another 5-hydroxytryptamine agonist (e.g., naratriptan, rizatriptan, sumatriptan, zolmitriptan) in the previous 24 hours
  • has taken ergotamine-containing or ergot-type medications (such as dihydroergotamine, ergotamine, or methysergide) in the previous 24 hours
  • is allergic to naratriptan or any of the components of the formulation
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